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Facile profiling of molecular heterogeneity by microfluidic digital melt

This work presents a digital microfluidic platform called HYPER-Melt (high-density profiling and enumeration by melt) for highly parallelized copy-by-copy DNA molecular profiling. HYPER-Melt provides a facile means of detecting and assessing sequence variations of thousands of individual DNA molecul...

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Detalles Bibliográficos
Autores principales: O’Keefe, Christine M., Pisanic, Thomas R., Zec, Helena, Overman, Michael J., Herman, James G., Wang, Tza-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157960/
https://www.ncbi.nlm.nih.gov/pubmed/30263958
http://dx.doi.org/10.1126/sciadv.aat6459