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Facile profiling of molecular heterogeneity by microfluidic digital melt
This work presents a digital microfluidic platform called HYPER-Melt (high-density profiling and enumeration by melt) for highly parallelized copy-by-copy DNA molecular profiling. HYPER-Melt provides a facile means of detecting and assessing sequence variations of thousands of individual DNA molecul...
Autores principales: | O’Keefe, Christine M., Pisanic, Thomas R., Zec, Helena, Overman, Michael J., Herman, James G., Wang, Tza-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157960/ https://www.ncbi.nlm.nih.gov/pubmed/30263958 http://dx.doi.org/10.1126/sciadv.aat6459 |
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