A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Brain function depends on interaction of diverse cell types whose gene expression and identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major epigenetic modifications, methylcytosine (mC) and hydroxymethylcytosine (hmC), yet their cell type–specific landscapes and re...

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Detalles Bibliográficos
Autores principales: Kozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157969/
https://www.ncbi.nlm.nih.gov/pubmed/30263963
http://dx.doi.org/10.1126/sciadv.aau6190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157969/
https://www.ncbi.nlm.nih.gov/pubmed/30263963
http://dx.doi.org/10.1126/sciadv.aau6190

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