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A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons
Brain function depends on interaction of diverse cell types whose gene expression and identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major epigenetic modifications, methylcytosine (mC) and hydroxymethylcytosine (hmC), yet their cell type–specific landscapes and re...
Autores principales: | Kozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157969/ https://www.ncbi.nlm.nih.gov/pubmed/30263963 http://dx.doi.org/10.1126/sciadv.aau6190 |
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