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Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature

BACKGROUND: Tumor-specific isoforms generated by alternative splicing (AS) are demonstrated to contribute to tumor progression and can represent potential biomarkers. NOVA2 is an AS factor that in physiological conditions regulates endothelial cells’ (ECs) polarity and vessel lumen maturation, likel...

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Detalles Bibliográficos
Autores principales: Gallo, Stefania, Arcidiacono, Maria Vittoria, Tisato, Veronica, Piva, Roberta, Penolazzi, Letizia, Bosi, Cristina, Feo, Carlo V, Gafà, Roberta, Secchiero, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157992/
https://www.ncbi.nlm.nih.gov/pubmed/30275709
http://dx.doi.org/10.2147/OTT.S171678