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Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy

PURPOSE: NVP-BEZ235 is a recently developed dual inhibitor of PI3K and mTOR and shows good inhibitory effects on several types of tumors. However, the efficacy of NVP-BEZ235 on gastric cancer therapy remains unclear. This study aimed to investigate the potential of NVP-BEZ235 as a new agent to enhan...

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Detalles Bibliográficos
Autores principales: Li, Liangqing, Zhang, Shengwei, Xie, Diya, Chen, Hui, Zheng, Xuelan, Pan, Dun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158000/
https://www.ncbi.nlm.nih.gov/pubmed/30275715
http://dx.doi.org/10.2147/OTT.S172957