Cargando…

Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation

Recent work suggests extensive adaptation of transposable elements (TEs) for host gene regulation. However, high numbers of integrations typical of TEs, coupled with sequence divergence within families, have made systematic interrogation of the regulatory contributions of TEs challenging. Here, we e...

Descripción completa

Detalles Bibliográficos
Autores principales: Fuentes, Daniel R, Swigut, Tomek, Wysocka, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158008/
https://www.ncbi.nlm.nih.gov/pubmed/30070637
http://dx.doi.org/10.7554/eLife.35989