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Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells

OBJECTIVE: Insulin-like peptide-5 (INSL5) is an orexigenic gut hormone found in a subset of colonic and rectal enteroendocrine L-cells together with the anorexigenic hormones glucagon-like peptide-1 (GLP-1) and peptideYY (PYY). Unlike GLP-1 and PYY, INSL5 levels are elevated by calorie restriction,...

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Detalles Bibliográficos
Autores principales: Billing, Lawrence J., Smith, Christopher A., Larraufie, Pierre, Goldspink, Deborah A., Galvin, Sam, Kay, Richard G., Howe, Jonathan D., Walker, Ryan, Pruna, Mihai, Glass, Leslie, Pais, Ramona, Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158034/
https://www.ncbi.nlm.nih.gov/pubmed/30104166
http://dx.doi.org/10.1016/j.molmet.2018.07.011