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Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection
Cellular susceptibility to viral infections is in part determined by the presence of a host cellular receptor. Here we use murine norovirus as a model to uncover an unappreciated connection between an intracellular lipid biosynthetic enzyme and a receptor conformation permissive for viral infection....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158067/ https://www.ncbi.nlm.nih.gov/pubmed/30127493 http://dx.doi.org/10.1038/s41564-018-0221-8 |