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B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen

Analysis of non‐Gal antibody induced after pig‐to‐baboon cardiac xenotransplantation identified the glycan produced by porcine beta‐1,4‐N‐acetyl‐galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen. The porcine B4GALNT2 enzyme is homologous to the human enzyme, which...

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Detalles Bibliográficos
Autores principales: Byrne, Guerard, Ahmad‐Villiers, Saadullah, Du, Zeji, McGregor, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158069/
https://www.ncbi.nlm.nih.gov/pubmed/29604134
http://dx.doi.org/10.1111/xen.12394