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Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis

Antigens (Ags) in Mycobacterium tuberculosis (Mtb) that are constitutively expressed, overexpressed during growth, essential for survival, and highly conserved may be good vaccine targets if they induce the appropriate anti-Mtb Th1 immune response. In this context, stress response-related antigens o...

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Detalles Bibliográficos
Autores principales: Kim, Woo Sik, Kim, Jong-Seok, Kim, Hong Min, Kwon, Kee Woong, Eum, Seok-Yong, Shin, Sung Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158166/
https://www.ncbi.nlm.nih.gov/pubmed/30258084
http://dx.doi.org/10.1038/s41598-018-32799-z