NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration

The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region an...

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Detalles Bibliográficos
Autores principales: Kathuria, Hasmeena, Millien, Guetchyn, McNally, Liam, Gower, Adam C., Tagne, Jean-Bosco, Cao, Yuxia, Ramirez, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158174/
https://www.ncbi.nlm.nih.gov/pubmed/30258080
http://dx.doi.org/10.1038/s41598-018-32793-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158174/
https://www.ncbi.nlm.nih.gov/pubmed/30258080
http://dx.doi.org/10.1038/s41598-018-32793-5

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