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NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration
The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region an...
Autores principales: | Kathuria, Hasmeena, Millien, Guetchyn, McNally, Liam, Gower, Adam C., Tagne, Jean-Bosco, Cao, Yuxia, Ramirez, Maria I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158174/ https://www.ncbi.nlm.nih.gov/pubmed/30258080 http://dx.doi.org/10.1038/s41598-018-32793-5 |
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