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Multi-omics integrative analysis with genome-scale metabolic model simulation reveals global cellular adaptation of Aspergillus niger under industrial enzyme production condition

Oxygen limitation is regarded as a useful strategy to improve enzyme production by mycelial fungus like Aspergillus niger. However, the intracellular metabolic response of A. niger to oxygen limitation is still obscure. To address this, the metabolism of A. niger was studied using multi-omics integr...

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Detalles Bibliográficos
Autores principales: Lu, Hongzhong, Cao, Weiqiang, Liu, Xiaoyun, Sui, Yufei, Ouyang, Liming, Xia, Jianye, Huang, Mingzhi, Zhuang, Yingping, Zhang, Siliang, Noorman, Henk, Chu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158188/
https://www.ncbi.nlm.nih.gov/pubmed/30258063
http://dx.doi.org/10.1038/s41598-018-32341-1