The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis

Collagen is the major structural component of cartilage, and mutations in the genes encoding type XI collagen are associated with severe skeletal dysplasias (fibrochondrogenesis and Stickler syndrome) and early-onset osteoarthritis (OA). The impact of the lack of type XI collagen on cell behaviour a...

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Detalles Bibliográficos
Autores principales: Lawrence, Elizabeth A., Kague, Erika, Aggleton, Jessye A., Harniman, Robert L., Roddy, Karen A., Hammond, Chrissy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158203/
https://www.ncbi.nlm.nih.gov/pubmed/30249781
http://dx.doi.org/10.1098/rstb.2017.0335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158203/
https://www.ncbi.nlm.nih.gov/pubmed/30249781
http://dx.doi.org/10.1098/rstb.2017.0335

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