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Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop

The severity of the 2014–2016 ebolavirus outbreak in West Africa expedited clinical development of therapeutics and vaccines though the countermeasures on hand were largely monospecific and lacked efficacy against other ebolavirus species that previously emerged. Recent studies indicate that ebolavi...

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Detalles Bibliográficos
Autores principales: Janus, Benjamin M., van Dyk, Nydia, Zhao, Xuelian, Howell, Katie A., Soto, Cinque, Aman, M. Javad, Li, Yuxing, Fuerst, Thomas R., Ofek, Gilad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158212/
https://www.ncbi.nlm.nih.gov/pubmed/30258051
http://dx.doi.org/10.1038/s41467-018-06113-4