Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

MiRNAs are part of the epigenetic machinery, and are also epigenetically modified by DNA methylation. MiRNAs regulate expression of different genes, so any alteration in their methylation status may affect their expression. We aimed to identify methylation differences in miRNA encoding genes in brea...

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Detalles Bibliográficos
Autores principales: Oltra, Sara S., Peña-Chilet, Maria, Vidal-Tomas, Victoria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158237/
https://www.ncbi.nlm.nih.gov/pubmed/30258192
http://dx.doi.org/10.1038/s41598-018-32393-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158237/
https://www.ncbi.nlm.nih.gov/pubmed/30258192
http://dx.doi.org/10.1038/s41598-018-32393-3

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