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TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9

TFPI-2 has been recognized as a potent tumor suppressor gene. Low expression of TFPI-2 results in enhanced growth and metastasis of a variety of human tumors. In the present study, we investigated the mechanism responsible for the tumor suppressive effect of TFPI-2. Overexpression of TFPI-2 decrease...

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Detalles Bibliográficos
Autores principales: Wang, Guangli, Huang, Wenhe, Li, Wei, Chen, Shaoying, Chen, Weibin, Zhou, Yanchun, Peng, Pei, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158255/
https://www.ncbi.nlm.nih.gov/pubmed/30258071
http://dx.doi.org/10.1038/s41598-018-32698-3