A short isoform of ATG7 fails to lipidate LC3/GABARAP

Autophagy is a degradation pathway important for cellular homeostasis. The E1-like enzyme ATG7 is a key component of the autophagy machinery, with the main function of mediating the lipidation of LC3/GABARAP during autophagosome formation. By analysing mRNA-sequencing data we found that in addition...

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Detalles Bibliográficos
Autores principales: Ogmundsdottir, M. H., Fock, V., Sooman, L., Pogenberg, V., Dilshat, R., Bindesbøll, C., Ogmundsdottir, H. M., Simonsen, A., Wilmanns, M., Steingrimsson, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158294/
https://www.ncbi.nlm.nih.gov/pubmed/30258106
http://dx.doi.org/10.1038/s41598-018-32694-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158294/
https://www.ncbi.nlm.nih.gov/pubmed/30258106
http://dx.doi.org/10.1038/s41598-018-32694-7

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