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A short isoform of ATG7 fails to lipidate LC3/GABARAP
Autophagy is a degradation pathway important for cellular homeostasis. The E1-like enzyme ATG7 is a key component of the autophagy machinery, with the main function of mediating the lipidation of LC3/GABARAP during autophagosome formation. By analysing mRNA-sequencing data we found that in addition...
Autores principales: | Ogmundsdottir, M. H., Fock, V., Sooman, L., Pogenberg, V., Dilshat, R., Bindesbøll, C., Ogmundsdottir, H. M., Simonsen, A., Wilmanns, M., Steingrimsson, E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158294/ https://www.ncbi.nlm.nih.gov/pubmed/30258106 http://dx.doi.org/10.1038/s41598-018-32694-7 |
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