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A combination of TLR-4 agonist and saponin adjuvants increases antibody diversity and protective efficacy of a recombinant West Nile Virus antigen

Members of the Flaviviridae family are the leading causes of mosquito-borne viral disease worldwide. While dengue virus is the most prevalent, the recent Zika virus outbreak in the Americas triggered a WHO public health emergency, and yellow fever and West Nile viruses (WNV) continue to cause region...

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Detalles Bibliográficos
Autores principales: Van Hoeven, Neal, Wiley, Steven, Gage, Emily, Fiore-Gartland, Andrew, Granger, Brian, Gray, Sean, Fox, Christopher, Clements, David E., Parks, D. Elliot, Winram, Scott, Stinchcomb, Dan T., Reed, Steven G., Coler, Rhea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158298/
https://www.ncbi.nlm.nih.gov/pubmed/30302281
http://dx.doi.org/10.1038/s41541-018-0077-1