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Sigma-1 Receptor-Modulated Neuroinflammation in Neurological Diseases

A large body of evidence indicates that sigma-1 receptors (Sig-1R) are important drug targets for a number of neuropsychiatric disorders. Sig-1Rs are enriched in central nervous system (CNS). In addition to neurons, both cerebral microglia and astrocytes express Sig-1Rs. Activation of Sig-1Rs is kno...

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Detalles Bibliográficos
Autores principales: Jia, Jia, Cheng, Jian, Wang, Cheng, Zhen, Xuechu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158303/
https://www.ncbi.nlm.nih.gov/pubmed/30294261
http://dx.doi.org/10.3389/fncel.2018.00314