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3′-End labeling of nucleic acids by a polymerase ribozyme
A polymerase ribozyme can be used to label the 3′ end of RNA or DNA molecules by incorporating a variety of functionalized nucleotide analogs. Guided by a complementary template, the ribozyme adds a single nucleotide that may contain a fluorophore, biotin, azide or alkyne moiety, thus enabling the d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158495/ https://www.ncbi.nlm.nih.gov/pubmed/29901762 http://dx.doi.org/10.1093/nar/gky513 |