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Two convergent pathways of DNA knotting in replicating DNA molecules as revealed by θ-curve analysis

During DNA replication in living cells some DNA knots are inadvertently produced by DNA topoisomerases facilitating progression of replication forks. The types of DNA knots formed are conditioned by the 3D organization of replicating DNA molecules. Therefore, by characterizing formed DNA knots it is...

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Detalles Bibliográficos
Autores principales: O’Donnol, Danielle, Stasiak, Andrzej, Buck, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158496/
https://www.ncbi.nlm.nih.gov/pubmed/29982678
http://dx.doi.org/10.1093/nar/gky559