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SOX9 has distinct regulatory roles in alternative splicing and transcription

SOX9 is known as a crucial transcription factor for various developmental processes and for tissue homeostasis. We examined here its potential role in alternative splicing by analyzing global splicing changes, using RNA-seq of colon tumor cells. We show that SOX9 knockdown alters the splicing of hun...

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Detalles Bibliográficos
Autores principales: Girardot, Michael, Bayet, Elsa, Maurin, Justine, Fort, Philippe, Roux, Pierre, Raynaud, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158501/
https://www.ncbi.nlm.nih.gov/pubmed/29901772
http://dx.doi.org/10.1093/nar/gky553