Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs

S-adenosyl-L-methionine-dependent 2′-O-methylati-on of the 3′-terminal nucleotide plays important roles in biogenesis of eukaryotic small non-coding RNAs, such as siRNAs, miRNAs and Piwi-interacting RNAs (piRNAs). Here we demonstrate that, in contrast to Mg(2+)/Mn(2+)-dependent plant and bacterial h...

Descripción completa

Detalles Bibliográficos
Autores principales: Mickutė, Milda, Nainytė, Milda, Vasiliauskaitė, Lina, Plotnikova, Alexandra, Masevičius, Viktoras, Klimašauskas, Saulius, Vilkaitis, Giedrius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158503/
https://www.ncbi.nlm.nih.gov/pubmed/29901763
http://dx.doi.org/10.1093/nar/gky514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158503/
https://www.ncbi.nlm.nih.gov/pubmed/29901763
http://dx.doi.org/10.1093/nar/gky514

Ejemplares similares