MBNL splicing activity depends on RNA binding site structural context

Muscleblind-like (MBNL) proteins are conserved RNA-binding factors involved in alternative splicing (AS) regulation during development. While AS is controlled by distribution of MBNL paralogs and isoforms, the affinity of these proteins for specific RNA-binding regions and their location within tran...

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Detalles Bibliográficos
Autores principales: Taylor, Katarzyna, Sznajder, Łukasz J, Cywoniuk, Piotr, Thomas, James D, Swanson, Maurice S, Sobczak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158504/
https://www.ncbi.nlm.nih.gov/pubmed/29955876
http://dx.doi.org/10.1093/nar/gky565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158504/
https://www.ncbi.nlm.nih.gov/pubmed/29955876
http://dx.doi.org/10.1093/nar/gky565

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