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Highly efficient RNAi and Cas9-based auto-cloning systems for C. elegans research

RNA interference (RNAi) technology used for the functional analysis of Caenorhabditis elegans genes frequently leads to phenotypes with low penetrance or even proves completely ineffective. The methods previously developed to solve this problem were built on mutant genetic backgrounds, such as those...

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Detalles Bibliográficos
Autores principales: Sturm, Ádám, Saskői, Éva, Tibor, Kovács, Weinhardt, Nóra, Vellai, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158509/
https://www.ncbi.nlm.nih.gov/pubmed/29924347
http://dx.doi.org/10.1093/nar/gky516