Analyses of a Ceftazidime-Avibactam-Resistant Citrobacter freundii Isolate Carrying bla(KPC-2) Reveals a Heterogenous Population and Reversible Genotype

A bla(KPC-2)-carrying Citrobacter freundii isolate developed ceftazidime-avibactam resistance during treatment with this agent. The initial and follow-up isolates exhibited ceftazidime-avibactam MICs of 4 and 64 µg/ml, respectively. Overexpression of AcrAB-TolC and porin alterations were detected in...

Descripción completa

Detalles Bibliográficos
Autores principales: Castanheira, Mariana, Arends, S. J. Ryan, Davis, Andrew P., Woosley, Leah N., Bhalodi, Amira A., MacVane, Shawn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158515/
https://www.ncbi.nlm.nih.gov/pubmed/30258039
http://dx.doi.org/10.1128/mSphere.00408-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158515/
https://www.ncbi.nlm.nih.gov/pubmed/30258039
http://dx.doi.org/10.1128/mSphere.00408-18

Ejemplares similares