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Analyses of a Ceftazidime-Avibactam-Resistant Citrobacter freundii Isolate Carrying bla(KPC-2) Reveals a Heterogenous Population and Reversible Genotype

A bla(KPC-2)-carrying Citrobacter freundii isolate developed ceftazidime-avibactam resistance during treatment with this agent. The initial and follow-up isolates exhibited ceftazidime-avibactam MICs of 4 and 64 µg/ml, respectively. Overexpression of AcrAB-TolC and porin alterations were detected in...

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Detalles Bibliográficos
Autores principales:	Castanheira, Mariana, Arends, S. J. Ryan, Davis, Andrew P., Woosley, Leah N., Bhalodi, Amira A., MacVane, Shawn H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158515/ https://www.ncbi.nlm.nih.gov/pubmed/30258039 http://dx.doi.org/10.1128/mSphere.00408-18

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