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Mesenchymal Stem Cell-Derived Extracellular Vesicles Improve the Renal Microvasculature in Metabolic Renovascular Disease in Swine

BACKGROUND: Extracellular vesicles (EVs) released from mesenchymal stem/stromal cells (MSCs) mediate their paracrine effect, but their efficacy to protect the microcirculation of the kidney is unknown. Using a novel swine model of unilateral renovascular disease (RVD) complicated by metabolic syndro...

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Detalles Bibliográficos
Autores principales: Eirin, Alfonso, Zhu, Xiang-Yang, Jonnada, Sreela, Lerman, Amir, van Wijnen, Andre J., Lerman, Lilach O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158551/
https://www.ncbi.nlm.nih.gov/pubmed/29954220
http://dx.doi.org/10.1177/0963689718780942