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Development of a Simple In Vitro Assay to Assess Digestion of the Extracellular Matrix of the Human Pancreas by Collagenase Enzyme Blends

Despite huge advances in the field of islet transplantation over the last two decades, current islet isolation methods remain suboptimal, with transplantable yields obtained in less than half of all pancreases processed worldwide. Successful islet isolation is dependent on the ability of collagenase...

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Detalles Bibliográficos
Autores principales: Spiers, Rebecca M., Cross, Sarah E., Brown, Helen L., Bateman, Paul A., Vaughan, Rebecca H., Hughes, Stephen J., Johnson, Paul R. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158553/
https://www.ncbi.nlm.nih.gov/pubmed/29954221
http://dx.doi.org/10.1177/0963689718779778