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Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

Mycobacteria remain an important problem worldwide, especially drug resistant human pathogens. Novel therapeutics are urgently needed to tackle both drug-resistant tuberculosis (TB) and difficult-to-treat infections with nontuberculous mycobacteria (NTM). Benzothiazole adamantyl amide had previously...

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Detalles Bibliográficos
Autores principales: De Groote, Mary A., Jarvis, Thale C., Wong, Christina, Graham, James, Hoang, Teresa, Young, Casey L., Ribble, Wendy, Day, Joshua, Li, Wei, Jackson, Mary, Gonzalez-Juarrero, Mercedes, Sun, Xicheng, Ochsner, Urs A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158578/
https://www.ncbi.nlm.nih.gov/pubmed/30294313
http://dx.doi.org/10.3389/fmicb.2018.02231