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Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens

Organoid cultures in 3D matrices are relevant models to mimic the complex in vivo environment that supports cell physiological and pathological behaviors. For instance, 3D epithelial organoids recapitulate numerous features of glandular tissues including the development of fully differentiated acini...

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Detalles Bibliográficos
Autores principales: Laperrousaz, Bastien, Porte, Stephanie, Gerbaud, Sophie, Härmä, Ville, Kermarrec, Frédérique, Hourtane, Virginie, Bottausci, Frédéric, Gidrol, Xavier, Picollet-D’hahan, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158603/
https://www.ncbi.nlm.nih.gov/pubmed/29394376
http://dx.doi.org/10.1093/nar/gky030