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Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens
Organoid cultures in 3D matrices are relevant models to mimic the complex in vivo environment that supports cell physiological and pathological behaviors. For instance, 3D epithelial organoids recapitulate numerous features of glandular tissues including the development of fully differentiated acini...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158603/ https://www.ncbi.nlm.nih.gov/pubmed/29394376 http://dx.doi.org/10.1093/nar/gky030 |