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INFERNO: inferring the molecular mechanisms of noncoding genetic variants

The majority of variants identified by genome-wide association studies (GWAS) reside in the noncoding genome, affecting regulatory elements including transcriptional enhancers. However, characterizing their effects requires the integration of GWAS results with context-specific regulatory activity an...

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Detalles Bibliográficos
Autores principales: Amlie-Wolf, Alexandre, Tang, Mitchell, Mlynarski, Elisabeth E, Kuksa, Pavel P, Valladares, Otto, Katanic, Zivadin, Tsuang, Debby, Brown, Christopher D, Schellenberg, Gerard D, Wang, Li-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158604/
https://www.ncbi.nlm.nih.gov/pubmed/30113658
http://dx.doi.org/10.1093/nar/gky686