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Thrombopoietin could protect cerebral tissue against ischemia-reperfusion injury by suppressing NF-κB and MMP-9 expression in rats

Objective: To determine the neuroprotective effects and underpinning mechanisms of thrombopoietin (TPO), Matrix Metalloproteinase-9(MMP-9) and Nuclear Factor-κB (NF-κB) after focal cerebral ischemia-reperfusion in rats. Methods: Male rats underwent 2 hours of right middle cerebral artery occlusion (...

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Detalles Bibliográficos
Autores principales: Wu, Wenjuan, Zhong, Wei, Lang, Bing, Hu, Zhiping, He, Jialin, Tang, Xiangqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158660/
https://www.ncbi.nlm.nih.gov/pubmed/30275761
http://dx.doi.org/10.7150/ijms.27543