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B355252, A Novel Small Molecule, Confers Neuroprotection Against Cobalt Chloride Toxicity In Mouse Hippocampal Cells Through Altering Mitochondrial Dynamics And Limiting Autophagy Induction

Cerebral hypoxia as often occurs in cases of stroke, hemorrhage, or other traumatic brain injuries, is one of the leading causes of death worldwide and a main driver of disabilities in the elderly. Using a chemical mimetic of hypoxia, cobalt chloride (CoCl(2)), we tested the ability of a novel small...

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Detalles Bibliográficos
Autores principales: Chimeh, Uchechukwu, Zimmerman, Mary Ann, Gilyazova, Nailya, Li, P. Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158673/
https://www.ncbi.nlm.nih.gov/pubmed/30275767
http://dx.doi.org/10.7150/ijms.24702