AGK2, A SIRT2 Inhibitor, Inhibits Hepatitis B Virus Replication In Vitro And In Vivo

Sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide (NAD( +))-dependent class III histone deacetylase. We have reported that HBx (hepatitis B virus X protein)-elevated SIRT2 promotes HBV replication and hepatocarcinogenesis. However, the potential anti-HBV effect of AGK2, a selective inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hai-Bo, Jiang, Hui, Cheng, Sheng-Tao, Hu, Zhong-Wen, Ren, Ji-Hua, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158674/
https://www.ncbi.nlm.nih.gov/pubmed/30275764
http://dx.doi.org/10.7150/ijms.26125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158674/
https://www.ncbi.nlm.nih.gov/pubmed/30275764
http://dx.doi.org/10.7150/ijms.26125

Ejemplares similares