Cargando…

AGK2, A SIRT2 Inhibitor, Inhibits Hepatitis B Virus Replication In Vitro And In Vivo

Sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide (NAD( +))-dependent class III histone deacetylase. We have reported that HBx (hepatitis B virus X protein)-elevated SIRT2 promotes HBV replication and hepatocarcinogenesis. However, the potential anti-HBV effect of AGK2, a selective inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Hai-Bo, Jiang, Hui, Cheng, Sheng-Tao, Hu, Zhong-Wen, Ren, Ji-Hua, Chen, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158674/ https://www.ncbi.nlm.nih.gov/pubmed/30275764 http://dx.doi.org/10.7150/ijms.26125

Ejemplares similares

Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis
por: Bhaskar, Ashima, et al.
Publicado: (2023)

Interleukin-34 inhibits hepatitis B virus replication in vitro and in vivo
por: Cheng, Sheng-Tao, et al.
Publicado: (2017)

AGK cutting rules and perturbative QCD
por: Treleani, D
Publicado: (1994)

Glauber theory, unitarity and the AGK cancellation
por: Bertocchi, L, et al.
Publicado: (1977)

SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors α
por: Jiang, Hui, et al.
Publicado: (2019)

Multiple Scattering at HERA and at LHC: Remarks on the AGK Rules
por: Bartels, J
Publicado: (2005)

Up‐regulated acylglycerol kinase (AGK) expression associates with gastric cancer progression through the formation of a novel YAP1‐AGK–positive loop
por: Huang, Shanshan, et al.
Publicado: (2020)

AGK regulates the progression to NASH by affecting mitochondria complex I function
por: Ding, Nan, et al.
Publicado: (2022)

Characterization of silver–kaolinite (AgK): an adsorbent for long-lived (129)I species
por: Sadasivam, Sivachidambaram, et al.
Publicado: (2016)

AGK‐BRAF gene fusion is a recurrent event in sporadic pediatric thyroid carcinoma
por: Cordioli, Maria Isabel C. V., et al.
Publicado: (2016)

Case Report: Two Chinese Infants of Sengers Syndrome Caused by Mutations in AGK Gene
por: Wang, Benzhen, et al.
Publicado: (2021)

Novel Loss of Function in the AGK Gene: Rare Cause of End-Stage Heart Failure
por: Das, Bibhuti B., et al.
Publicado: (2019)

AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-κB signaling pathway in hepatocellular carcinoma
por: Cui, Yanmei, et al.
Publicado: (2014)

Characterization of a Novel Splicing Variant in Acylglycerol Kinase (AGK) Associated with Fatal Sengers Syndrome
por: Barbosa-Gouveia, Sofia, et al.
Publicado: (2021)

ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma
por: Sun, Yan, et al.
Publicado: (2023)

SIRT2 Promotes HBV Transcription and Replication by Targeting Transcription Factor p53 to Increase the Activities of HBV Enhancers and Promoters
por: Wu, Dai-Qing, et al.
Publicado: (2022)

SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo
por: Jiao, Fangzhou, et al.
Publicado: (2022)

Niacin analogue, 6-Aminonicotinamide, a novel inhibitor of hepatitis B virus replication and HBsAg production
por: Ren, Fang, et al.
Publicado: (2019)

Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro
por: Murray, Jackelyn, et al.
Publicado: (2021)

The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo
por: Todt, Daniel, et al.
Publicado: (2018)

Sengers syndrome: six novel AGK mutations in seven new families and review of the phenotypic and mutational spectrum of 29 patients
por: Haghighi, Alireza, et al.
Publicado: (2014)

Role of SIRT1 in Hepatic Encephalopathy: In Vivo and In Vitro Studies Focusing on the NLRP3 Inflammasome
por: Jiao, Fangzhou, et al.
Publicado: (2021)

Effects of Resveratrol on Hepatitis B Virus Replication: In vitro and in vivo Experiments
por: Pan, Peipei, et al.
Publicado: (2022)

NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma
por: Zhou, Hong-Zhong, et al.
Publicado: (2019)

Quercetin inhibits rhinovirus replication in vitro and in vivo
por: Ganesan, Shyamala, et al.
Publicado: (2012)

Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression
por: Ren, Ji-Hua, et al.
Publicado: (2016)

Artemisinin Analogues as Potent Inhibitors of In Vitro Hepatitis C Virus Replication
por: Obeid, Susan, et al.
Publicado: (2013)

Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
por: Dai, Zhi-Jun, et al.
Publicado: (2012)

Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo
por: Li, Dan, et al.
Publicado: (2017)

Joint Guideline of the OEGGG, AGO, AGK and ÖGZ on the Diagnosis and Treatment of Cervical Intraepithelial Neoplasia and Appropriate Procedures When Cytological Specimens Are Unsatisfactory
por: Reich, Olaf, et al.
Publicado: (2018)

Circ_0008068 facilitates the oral squamous cell carcinoma development by microRNA-153-3p/acylgycerol kinase (AGK) axis
por: Long, Yuanyuan, et al.
Publicado: (2022)

Adeno-Associated Viruses Serotype 2-Mediated RNA Interference Efficiently Inhibits Rabies Virus Replication In Vitro and In Vivo
por: WU, Hong-Xia, et al.
Publicado: (2013)

Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro
por: Xiao, Jie, et al.
Publicado: (2016)

KAT2A Promotes Hepatitis B Virus Transcription and Replication Through Epigenetic Regulation of cccDNA Minichromosome
por: Qin, Yi-Ping, et al.
Publicado: (2022)

Atazanavir Is a Competitive Inhibitor of SARS-CoV-2 M(pro), Impairing Variants Replication In Vitro and In Vivo
por: Chaves, Otávio Augusto, et al.
Publicado: (2021)

Inhibition of foot-and-mouth disease virus replication in vitro and in vivo by small interfering RNA
por: Pengyan, Wang, et al.
Publicado: (2008)

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
por: Smith, Jesse J, et al.
Publicado: (2009)

Role and Functional Domain of Hepatitis B Virus X Protein in Regulating HBV Transcription and Replication in Vitro and in Vivo
por: Gong, Dao-Yin, et al.
Publicado: (2013)

SIRT1 inhibits apoptosis in in vivo and in vitro models of spinal cord injury via microRNA-494
por: Yu, Xiaobing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_50jsgis8r1ch4seoscr0njpck5