Structural dynamics of propeller loop: towards folding of RNA G-quadruplex

We have carried out an extended set of standard and enhanced-sampling MD simulations (for a cumulative simulation time of 620 μs) with the aim to study folding landscapes of the rGGGUUAGGG and rGGGAGGG parallel G-hairpins (PH) with propeller loop. We identify folding and unfolding pathways of the PH...

Descripción completa

Detalles Bibliográficos
Autores principales: Havrila, Marek, Stadlbauer, Petr, Kührová, Petra, Banáš, Pavel, Mergny, Jean-Louis, Otyepka, Michal, Šponer, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158699/
https://www.ncbi.nlm.nih.gov/pubmed/30165550
http://dx.doi.org/10.1093/nar/gky712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158699/
https://www.ncbi.nlm.nih.gov/pubmed/30165550
http://dx.doi.org/10.1093/nar/gky712

Ejemplares similares