Modification of the aminopyridine unit of 2′-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences

The antigene strategy based on site-specific recognition of duplex DNA by triplex DNA formation has been exploited in a wide range of biological activities. However, specific triplex formation is mostly restricted to homo-purine strands within the target duplex DNA, due to the destabilizing effect o...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Taniguchi, Yosuke, Okamura, Hidenori, Sasaki, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158708/
https://www.ncbi.nlm.nih.gov/pubmed/30102410
http://dx.doi.org/10.1093/nar/gky704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158708/
https://www.ncbi.nlm.nih.gov/pubmed/30102410
http://dx.doi.org/10.1093/nar/gky704

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