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Global DNA methylation synergistically regulates the nuclear and mitochondrial genomes in glioblastoma cells
Replication of mitochondrial DNA is strictly regulated during differentiation and development allowing each cell type to acquire its required mtDNA copy number to meet its specific needs for energy. Undifferentiated cells establish the mtDNA set point, which provides low numbers of mtDNA copy but su...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158714/ https://www.ncbi.nlm.nih.gov/pubmed/29722878 http://dx.doi.org/10.1093/nar/gky339 |