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Diffusion of ring-shaped proteins along DNA: case study of sliding clamps

Several DNA-binding proteins, such as topoisomerases, helicases and sliding clamps, have a toroidal (i.e. ring) shape that topologically traps DNA, with this quality being essential to their function. Many DNA-binding proteins that function, for example, as transcription factors or enzymes were show...

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Detalles Bibliográficos
Autores principales: Daitchman, Dina, Greenblatt, Harry M, Levy, Yaakov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158715/
https://www.ncbi.nlm.nih.gov/pubmed/29860305
http://dx.doi.org/10.1093/nar/gky436