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Butein suppresses hepatocellular carcinoma growth via modulating Aurora B kinase activity

Aurora B is aberrantly expressed in various tumors and shown to be a promising target for cancer therapy. Butein, a chalcone isolated from Rhus cerniciflua, has demonstrated antitumor activities in different cancers. In this study, we aimed to validate whether Aurora B kinase was the direct target o...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanfeng, Li, Ming, Yu, Xinyou, Liu, Ting, Li, Tian, Zhou, Li, Liu, Wenbin, Li, Wei, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158728/
https://www.ncbi.nlm.nih.gov/pubmed/30263005
http://dx.doi.org/10.7150/ijbs.25334