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MiR-490-3p inhibits osteogenic differentiation in thoracic ligamentum flavum cells by targeting FOXO1

Thoracic ossification of the ligamentum flavum (TOLF) is a rare heterotopic ossification of spinal ligaments, which is the major cause of thoracic spinal canal stenosis and myelopathy. In this study, the roles of miR-490-3p and forkhead box O1 (FOXO1) in osteogenesis of human thoracic ligamentum fla...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxi, Qu, Xiaochen, Meng, Xiangyu, Li, Mengtao, Fan, Dongwei, Fan, Tianqi, Huang, Ann Y, Chen, Zhongqiang, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158729/
https://www.ncbi.nlm.nih.gov/pubmed/30262997
http://dx.doi.org/10.7150/ijbs.26686