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MicroRNA485-3p negatively regulates the transcriptional co-repressor CtBP1 to control the oncogenic process in osteosarcoma cells

Carboxyl-terminal binding protein 1 (CtBP1), a well-known transcriptional co-repressor, is highly expressed in a number of cancer types. However, it is still absent in osteosarcoma cells. Here, we found that CtBP1, but not CtBP2, is overexpressed in invasive osteosarcoma tissues and cells. The overe...

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Detalles Bibliográficos
Autores principales: Du, Kaili, Zhang, Xinliang, Lou, Zhenkai, Guo, Peiyu, Zhang, Fan, Wang, Bing, Chen, Lingqiang, Zhang, Chunqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158736/
https://www.ncbi.nlm.nih.gov/pubmed/30262996
http://dx.doi.org/10.7150/ijbs.26335