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Control of mRNA decapping by autoinhibition

5′ mediated cytoplasmic RNA decay is a conserved cellular process in eukaryotes. While the functions of the structured core domains in this pathway are well-studied, the role of abundant intrinsically disordered regions (IDRs) is lacking. Here we reconstitute the Dcp1:Dcp2 complex containing a porti...

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Detalles Bibliográficos
Autores principales: Paquette, David R, Tibble, Ryan W, Daifuku, Tristan S, Gross, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158755/
https://www.ncbi.nlm.nih.gov/pubmed/29618050
http://dx.doi.org/10.1093/nar/gky233