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Dynamic assessment of tau immunotherapies in the brains of live animals by two-photon imaging

Our original findings, showing the effectiveness of active and passive tau immunizations in mouse models, have now been confirmed and extended by many groups, with several clinical trials underway in Alzheimer's disease and progressive supranuclear palsy. Here, we report on a unique and sensiti...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Lin, Yan, Gu, Jiaping, Sigurdsson, Einar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158769/
https://www.ncbi.nlm.nih.gov/pubmed/30146345
http://dx.doi.org/10.1016/j.ebiom.2018.08.041