Cargando…

Translating GWAS in rheumatic disease: approaches to establishing mechanism and function for genetic associations with ankylosing spondylitis

Ankylosing spondylitis (AS) is a highly heritable chronic inflammatory arthritis characterized by osteoproliferation, fusion of affected joints and systemic manifestations. Many disease associations for AS have been reported through genome-wide association studies; however, identifying modulated gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Osgood, Julie A, Knight, Julian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158798/
https://www.ncbi.nlm.nih.gov/pubmed/29741584
http://dx.doi.org/10.1093/bfgp/ely015